Showing posts with label Major depressive disorder. Show all posts
Showing posts with label Major depressive disorder. Show all posts

Monday, November 14, 2011

Coffee May Protect Women from Depression



Here, a large study involving nearly 51,000 women found that drinking four or more cups of coffee a day appears to lower the long-term risk of depression. Researchers from the Harvard School of Public Health followed participants in the long-running Nurses' Health Study to see what effect coffee would have on the risk of depression. At the study's outset, none of the women reported being depressed, and none were taking antidepressants.

As the study progressed, results indicated that women who drank four or more cups of coffee daily had a 20 percent lower risk of depression than those who drank one cup or less daily. Those who consumed two to three cups had a 15 percent lower risk of depression. Too much caffeine can jangle the nerves, boost anxiety levels, and contribute to other health risks, but caffeine does have well-known short-term positive effects on mood - it can provide an energy boost and increase alertness. Until now, however, little has been known about its possible long-term effects on mood. The study was published in the September 26 issue of the Archives of Internal Medicine.

Saturday, October 15, 2011

Smoking Pot Might Up Depression Risk in Vulnerable Teens

Smoking Pot Might Up Depression Risk in Vulnerable Teens

Smoking marijuana increases the risk of depression in youngsters who are genetically susceptible to the mental health disorder, according to a new study.
About two-thirds of the population have the variant of the serotonin gene (5-HTT) that increases vulnerability to depression, said the researchers at Radboud University Nijmegen in the Netherlands.
They analyzed five years of data collected from 428 families with two adolescent children each. The youngsters provided yearly information about their behavior and depressive symptoms.
The study found a strong association between marijuana use and an increase in depressive symptoms among those with the gene variant.
"The effect is robust. It still remains, even if you take into account a series of other variables that could cause the effect, such as smoking behavior, alcohol use, upbringing, personality and socioeconomic status," the researchers said in a university release.
"Some people might think that young people with a disposition for depression would start smoking cannabis as a form of self-medication, and that the presence of depressive symptoms is therefore the cause of cannabis use. However, in the longer term that is definitely not the case. Although the immediate effect of cannabis may be pleasant and cause a feeling of euphoria, in the longer term we observe that cannabis use leads to an increase in depressive symptoms in young people with this specific genotype," the researchers said.
The study appears online in the journal Addiction Biology.
-- Robert Preidt

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Tuesday, September 27, 2011

Coffee Lowers Depression Risk In Older Females


The more coffee an older woman drinks the lower her risk of depression is, researchers from the Harvard School of Public Health reported in Archives of Internal Medicine. The researchers stressed that theirs was an observational study, and can only suggest the possibility of coffee's protective effect, rather that prove that it reduces depression risk.
The authors explained that about 80% of caffeine consumption worldwide is in the form of coffee - it is the most commonly used CNS (central nervous system) stimulant.
Previous studies have looked at associations between coffee drinking and depression risk - one prospective study among young adult males suggested coffee consumption might be linked to depression risk. Depression is often a long-term (chronic) condition that has a tendency to come back, it affects twice as many females as males. Experts say that about 1 in every 5 women in the United States will suffer from depression at some point in their lives.
The authors wrote that:
"(the) identification of risk factors for depression among women and the development of new preventive strategies are, therefore, a public health priority."

Michel Lucas, Ph.D., R.D. and team set out to determine whether the consumption of coffee or some drinks containing caffeine might be linked to depression risk.
They gathered data on 50,737 women, average age 63 years; none of them had depression when the study began. They had all participated in the Nurses' Health Study. They were prospectively followed up until June 2006. Questionnaires had asked them what their caffeine consumption was from 1980 to 2004. The researchers had data on how often they consumed caffeinated and non-caffeinated coffee, nonherbal tea, caffeinated sodas (sugared or low calorie), all types of caffeine-free soft drinks, and chocolate during a twelve month period before filling in each questionnaire.
In this study, depression was defined as having a diagnosis of clinical depression and being prescribed regular antidepressants during the previous two years.
They analyzed the cumulative consumption over a period and then looked at a two-year latency period. For example, caffeine consumption data from 1980 through 1994 were used to predict clinical depression rates from 1996 through 1998.
They identified 2,607 new diagnoses of depression during the 10-year follow up period 1996-2006.

Below are some highlighted data from their findings:
  • Women who consumed two to three cups of caffeinated coffee per day were 15% less likely to develop depression compared to those who drank a maximum of one cup of caffeinated coffee per week
  • Women who drank at least 4 cups per day had a 20% lower risk than the maximum 1 cup per week females
  • Those who consumed at least 550mg per day of caffeine had a 20% lower risk of developing depression compared to the women whose daily consumption was 100mg or less per day
  • The consumption of decaffeinated coffee had no impact on depression risk
The authors wrote:
"In this large prospective cohort of older women free of clinical depression or severe depressive symptoms at baseline, risk of depression decreased in a dose-dependent manner with increasing consumption of caffeinated coffee."


They added:

"(this observational study) cannot prove that caffeine or caffeinated coffee reduces the risk of depression but only suggests the possibility of such a protective effect."


Further studies are required to confirm their findings, as well as to determine what impact regular caffeine consumption might have on the general population, and whether it could be used to treat depression.

Caffeine's effect on some animals

Most humans can drink caffeine relatively safely. However, it is very toxic to some animals, such as birds and dogs. Caffeine can have some weird effects on spiders, as can be seen in the picture below.


Caffeine effect on spider
The spider on caffeine makes a pretty useless web


Written by Christian Nordqvist

 
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